Can You Have Grapefruit With Statins
Grapefruit can increase the side effects of some statin cholesterol medications causing muscle damage.
Can you have grapefruit with statins. For example if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol too much of the drug may stay in your body increasing your risk for liver and muscle. Grapefruit juice increases the level of simvastatin in your blood and makes side effects more likely. Doctors warn against consuming Grapefruit juice if you take certain types of medication such as statins which are metabolized by the CYP3A4 enzyme.
Grapefruit juice inhibits this enzyme so the liver produces less of it and this affects the action of those drugs they will be less effective. It is known that grapefruits contain a group of chemicals furanocoumarins which can alter drug metabolism the amount of time it takes for a drug to be broken down by the body. Grapefruit juice contains a chemical that can interfere with the enzymes that break down metabolize the statins in your digestive system.
But some researchers arent so sure. You only need to avoid grapefruit if your doctor prescribes. However how much grapefruit juice one needs to consume to produce a clinically significant drug interaction isnt entirely known.
Generally its a healthy food that contains fiber vitamin C. Dont take these interactions lightly. Grapefruit juice may increase the plasma concentrations of atorvastatin.
Ive heard that people shouldnt drink grapefruit juice if theyre taking a statin. One misconception is that you shouldnt mix grapefruit with any statin drug. Drugs and food that interact with statins.
The furanocoumarins in grapefruit may affect how the body processes other medications such as allergy medicine according. Grapefruit or grapefruit juice affects some statins. Do not drink grapefruit juice if youre taking simvastatin.